产品货号：
JN0855
中文名称：
重组人泛素结合酶E2-G2(UBCE2G2)
英文名称：
Recombinant Human Ubiquitin-Conjugating Enzyme E2 G2
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Leu165在N端带有GST标签。
UBE2G2质量控制：＞95%(还原性SDS-PAGE)
UBE2G2制剂：液体
UBE2G2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于UBE2G2：
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s.
相关搜索：重组人泛素结合酶E2-G2(UBCE2G2)
UBE2G2质量控制：＞95%(还原性SDS-PAGE)
UBE2G2制剂：液体
UBE2G2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于UBE2G2：
Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60% and 100% sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 molecules into close proximity which allows for Ub transfer between neighboring E2s.
相关搜索：重组人泛素结合酶E2-G2(UBCE2G2)